{"product_id":"cd298-atp1b3-rabbit-polymab®-a19637pm","title":"CD298\/ATP1B3 Rabbit PolymAb® - A19637PM","description":"\u003cp\u003eCD298\/ATP1B3 Rabbit PolymAb®\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A19637PM-20, A19637PM-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the family of Na+\/K+ and H+\/K+ ATPases beta chain proteins, and to the subfamily of Na+\/K+ -ATPases. Na+\/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The beta subunit regulates, through assembly of alpha\/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+\/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, IF-P, IHC-P, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 22kDa\/32kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 31-43kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 483\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P54709\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD298; ATPB-3; ATP1B3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1500 - 1:3000 IF\/ICC, 1:200 - 1:800 IF-P, 1:200 - 1:800 IHC-P, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction, Endocrine Metabolism, Immunology Inflammation, CDs.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: ATP1B3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189786370227,"sku":"A19637PM-20","price":165.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189786402995,"sku":"A19637PM-100","price":431.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_21490fb1-4c13-4aea-afef-4dde2d18dad4.png?v=1766435429","url":"https:\/\/afsbio.com\/products\/cd298-atp1b3-rabbit-polymab%c2%ae-a19637pm","provider":"AFSBio Inc.","version":"1.0","type":"link"}