{"product_id":"cd298-polyclonal-antibody-bt-ap01446","title":"CD298 Polyclonal Antibody - BT-AP01446","description":"\u003cp\u003eCD298 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01446-20, BT-AP01446-50, BT-AP01446-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ATPase Na+\/K+ transporting subunit beta 3 encoded by ATP1B3 belongs to the family of Na+\/K+ and H+\/K+ ATPases beta chain proteins, and to the subfamily of Na+\/K+ -ATPases. Na+\/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha\/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+\/K+ -ATPase is encoded by multiple genes. ATP1B3 encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for ATP1B3, and it is located on chromosome 2.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ATP1B3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD298 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31513\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P54709; Mouse: P97370\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATP1B3; Sodium\/potassium-transporting ATPase subunit beta-3; Sodium\/potassium-dependent ATPase subunit beta-3; ATPB-3; CD298\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 483\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240174477491,"sku":"BT-AP01446-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240174510259,"sku":"BT-AP01446-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240174543027,"sku":"BT-AP01446-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c3bcabe3-0756-4714-8e61-ef9a662c3dbd.png?v=1769404594","url":"https:\/\/afsbio.com\/products\/cd298-polyclonal-antibody-bt-ap01446","provider":"AFSBio Inc.","version":"1.0","type":"link"}