{"product_id":"cd3-ε-polyclonal-antibody-ra20479","title":"CD3-ε Polyclonal Antibody - RA20479","description":"\u003cp\u003eCD3-ε Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA20479-50, RA20479-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD3e molecule (CD3E) Homo sapiens The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha\/beta and gamma\/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3\/Leu-4 epsilon chain; CD antigen CD3e\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 916\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 21\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P07766\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120670531763,"sku":"RA20479-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120670564531,"sku":"RA20479-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_28282c10-9b2e-40cb-9390-a630c6649926.png?v=1773369235","url":"https:\/\/afsbio.com\/products\/cd3-%ce%b5-polyclonal-antibody-ra20479","provider":"AFSBio Inc.","version":"1.0","type":"link"}