{"product_id":"cd3-epsilon-polyclonal-antibody-bt-ap01498","title":"CD3-Epsilon Polyclonal Antibody - BT-AP01498","description":"\u003cp\u003eCD3-Epsilon Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01498-20, BT-AP01498-50, BT-AP01498-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD3e molecule encoded by CD3E is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha\/beta and gamma\/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD3E\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD3-epsilon Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 23147\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P07766; Mouse: P22646\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3\/Leu-4 epsilon chain; CD3e\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 916\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240178213043,"sku":"BT-AP01498-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240178245811,"sku":"BT-AP01498-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240178278579,"sku":"BT-AP01498-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ec31c69c-c9cc-4cff-b281-3b3f581dd21b.png?v=1769404665","url":"https:\/\/afsbio.com\/products\/cd3-epsilon-polyclonal-antibody-bt-ap01498","provider":"AFSBio Inc.","version":"1.0","type":"link"}