{"product_id":"cd30-l-polyclonal-antibody-bt-ap01467","title":"CD30-L Polyclonal Antibody - BT-AP01467","description":"\u003cp\u003eCD30-L Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01467-20, BT-AP01467-50, BT-AP01467-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The tumor necrosis factor superfamily member 8 encoded by TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8\/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFSF8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD30-L Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 26017\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P32971; Mouse: P32972\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TNFSF8; CD30L; CD30LG; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD153\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 944; Mouse: 21949\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240175755443,"sku":"BT-AP01467-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240175788211,"sku":"BT-AP01467-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240175820979,"sku":"BT-AP01467-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5de3ead5-a5d0-490b-9fca-c039740b826e.png?v=1769404618","url":"https:\/\/afsbio.com\/products\/cd30-l-polyclonal-antibody-bt-ap01467","provider":"AFSBio Inc.","version":"1.0","type":"link"}