{"product_id":"cd30-l-q103-polyclonal-antibody-bs2746","title":"CD30-L (Q103) Polyclonal Antibody-BS2746","description":"\u003cp\u003eCD30-L (Q103) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers:BS2746-50, BS2746-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P32971\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, IF\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: IHC: 1:50~1:200\u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+\/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 26 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD30-L (Q103) polyclonal antibody detects endogenous levels of CD30-L protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003cbr\u003e\nAlternative Name: Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD153; TNFSF8; CD30L; CD30LG\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 80-130 of Human CD30-L.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42895071674547,"sku":"BS2746-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42895071707315,"sku":"BS2746-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_09a87b6e-e92e-4bb7-bb85-8fb4840aab2b.jpg?v=1702573261","url":"https:\/\/afsbio.com\/products\/cd30-l-q103-polyclonal-antibody-bs2746","provider":"AFSBio Inc.","version":"1.0","type":"link"}