{"product_id":"cd305-polyclonal-antibody-ncp0313p","title":"CD305 Polyclonal Antibody-NCP0313P","description":"\u003cp\u003eCD305 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0313P-50, NCP0313P-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q6GTX8\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:1000~1:2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: LAIR-1 is an inhibitory receptor that belongs to the Immunoglobulin superfamily. It has one extracellular Ig-like domain and an intracellular C-terminus with two ITIM (immunoreceptor tyrosine-based inhibitory motif) domains. It is found on peripheral mononuclear cells, including NK, T, and B cells, and is thought to play a negative regulatory role on the cytolytic function of these cells through signaling through collagen ligation. LAIR1 has been noted to be upregulated in renal cell carcinoma, and may play a role in expansion of Th17 cell populations in collagen-rich environments, such as in graft rejection tissue.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD305 polyclonal antibody detects endogenous levels of CD305 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 46 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD305 polyclonal antibody at 1:1000 dilution\u003cbr\u003e\n Lane 1: THP-1 whole cell lysate (30ug\u003cbr\u003e\n Lane 2: L02 cell membrane lysate (24ug)\u003cbr\u003e\n Lane 3: MCF-7 cell membrane lysate (24ug)\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Leukocyte-associated immunoglobulin-like receptor 1; LAIR-1; hLAIR1; LAIR1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD305.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987092181171,"sku":"NCP0313P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987092213939,"sku":"NCP0313P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_202a4f28-e4c5-4f15-ba69-fb93e385824b.jpg?v=1706008989","url":"https:\/\/afsbio.com\/products\/cd305-polyclonal-antibody-ncp0313p","provider":"AFSBio Inc.","version":"1.0","type":"link"}