{"product_id":"cd31-polyclonal-antibody-e-ab-70020","title":"CD31 Polyclonal Antibody - E-AB-70020","description":"\u003cp\u003eCD31 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70020-60, E-AB-70020-120, E-AB-70020-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD31\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Adhesion molecule; CD31; CD31 antigen; CD31 EndoCAM; EndoCAM; FLJ34100; FLJ58394; GPIIA; GPIIA'; PECA1; PECA1; Pecam 1; PECAM 1 CD31 EndoCAM; PECAM; PECAM-1; Pecam1; Platelet and endothelial cell adhesion molecule 1; Platelet endothelial cell adhesion molecule; Platelet\/endothelial cell adhesion molecule 1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P16284,Q08481,Q3SWT0\u003c\/p\u003e\n\n\u003cp\u003eBackground: Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis .\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.88 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD31\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 130kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 90\/130kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146501587123,"sku":"E-AB-70020-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146501619891,"sku":"E-AB-70020-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146501652659,"sku":"E-AB-70020-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1490f6a8-335a-4373-b3ed-e2c4b37b1751.png?v=1710296516","url":"https:\/\/afsbio.com\/products\/cd31-polyclonal-antibody-e-ab-70020","provider":"AFSBio Inc.","version":"1.0","type":"link"}