{"product_id":"cd321-polyclonal-antibody-ncp0316p","title":"CD321 Polyclonal Antibody-NCP0316P","description":"\u003cp\u003eCD321 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0316P-50, NCP0316P-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9Y624\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:2000~1:5000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Junctional Adhesion Molecule-A\/F11 Receptor (JAM-A\/F11R) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. JAM-A regulates multiple cellular processes, including tight junction assembly, epithelial-mesenchymal transition (EMT), leukocyte migration, virus binding, platelet activation, and angiogenesis.  Aberrant expression of JAM-A is correlated with poor patient prognosis in several human cancers. In a mouse model of atherosclerosis, an antagonistic peptide that inhibits JAM-A-expressing platelets from interacting with inflamed endothelial cells reduces atherosclerotic plaque formation.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD321 polyclonal antibody detects endogenous levels of CD321 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD321 polyclonal antibody at 1:2000 dilution\u003cbr\u003e\nLane1:HEK293T whole cell lysate(30ug)\u003cbr\u003e\nLane2:A549 whole cell lysate(30ug)\u003cbr\u003e\nLane3:HepG2 whole cell lysate(30ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 38 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD_antigen: CD321; F11R; JAM1; JCAM; UNQ264\/PRO301\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD321.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908703228083,"sku":"NCP0316P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908703260851,"sku":"NCP0316P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e9224460-bb7b-4b97-859f-11f67213c023.jpg?v=1703006023","url":"https:\/\/afsbio.com\/products\/cd321-polyclonal-antibody-ncp0316p","provider":"AFSBio Inc.","version":"1.0","type":"link"}