{"product_id":"cd324-e-cadherin-rabbit-pab-a24874","title":"CD324\/E-Cadherin Rabbit pAb - A24874","description":"\u003cp\u003eCD324\/E-Cadherin Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24874-20, A24874-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 98kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 135kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 12550\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P09803\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CDH1; Arc-1; CD324; CDHE; ECAD; LCAM; UVO; AA960649; ARC-1; E-cad; Ecad; L-CAM; Um; cadherin-1; CD324\/E-Cadherin\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Invasion and Metastasis, Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology \u0026amp; Developmental Biology, Apoptosis, Cell Cycle, Centrosome, Cell Adhesion, Cadherins, Tight Junctions, Cytoskeleton, Wnt\/β-Catenin Signaling Pathway, Immunology \u0026amp; Inflammation, CD markers, Neuroscience, Calcium Signaling.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Cdh1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189860098227,"sku":"A24874-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189860130995,"sku":"A24874-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_23e7a3da-4c8f-4ab5-976f-cf25101b9300.png?v=1766436939","url":"https:\/\/afsbio.com\/products\/cd324-e-cadherin-rabbit-pab-a24874","provider":"AFSBio Inc.","version":"1.0","type":"link"}