{"product_id":"cd338-monoclonal-antibody-bt-mca4425","title":"CD338 Monoclonal Antibody - BT-MCA4425","description":"\u003cp\u003eCD338 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4425-50, BT-MCA4425-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD338\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4H3C10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD338\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 75kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9UNQ0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, ABCG2, GOUT1, MXR-1, CDw338, UAQTL1, EST157481\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 9429\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238394945715,"sku":"BT-MCA4425-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238394978483,"sku":"BT-MCA4425-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_215ca820-d1b6-4a84-9339-34a0dbb623a9.png?v=1769379880","url":"https:\/\/afsbio.com\/products\/cd338-monoclonal-antibody-bt-mca4425","provider":"AFSBio Inc.","version":"1.0","type":"link"}