{"product_id":"cd34-monoclonal-antibody-mb65776","title":"CD34 Monoclonal Antibody-MB65776","description":"\u003cp\u003eCD34 Monoclonal Antibody\u003c\/p\u003e \n\n\u003cp\u003eCatalogue Numbers: MB65776-50, MB65776-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P28906\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IF (1\/50 - 1\/200)\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD34 is a type I transmembrane glycophosphoprotein expressed by hematopoietic stem\/progenitor cells, vascular endothelium and some fibroblasts. CD34 expression has been the hallmark used to identify hematopoietic stem cells for many years. CD34+ hematopoietic stem cells expand and differentiate into all the lymphohematopoietic lineages upon cytokine or growth factor stimulation and lose CD34 expression upon differentiation. However, recent studies performed in various laboratories conflict with that convention. The extracellular domain of CD34 is homologous to CD43, a protein involved in cell-cell adhesion, and CD34 has been shown to function as a negative regulator of cell adhesion. CD34 associates with CrkL but not CrkII, is a substrate for PKC, and activation of PKC is coupled with surface expression of CD34.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The monoclonal antibody  was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes human CD34\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Flow cytometric analysis of HEL cells using Anti-CD34 Antibody, followed by anti-mouse IgG PE.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 40 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Hematopoietic progenitor cell antigen CD34; CD antigen CD34\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Native purified human CD34.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908734521523,"sku":"MB65776-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908734554291,"sku":"MB65776-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bc9bcef6-d32d-4e7a-a20c-fe993b68899f.jpg?v=1703006436","url":"https:\/\/afsbio.com\/products\/cd34-monoclonal-antibody-mb65776","provider":"AFSBio Inc.","version":"1.0","type":"link"}