{"product_id":"cd34-polyclonal-antibody-bs90234","title":"CD34 Polyclonal Antibody-BS90234","description":"\u003cp\u003eCD34 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90234-50, BS90234-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P28906\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC IHC FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:2,000\u003cbr\u003e\nICC:1:200\u003cbr\u003e\nIHC:1:2,000-1:3,000\u003cbr\u003e\nFC:1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Peptide affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD34 polyclonal antibody detects endogenous levels of CD34 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 120 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of CD34 on different cell lysates using anti-CD34antibody at 1\/1000 dilution. \u003cbr\u003e\n Positive control: \u003cbr\u003e\n Lane 1: Human brain \u003cbr\u003e\n Lane 2: Mouse brain \u003cbr\u003e\n Lane 3: Mouse testis \u003cbr\u003e\n Lane 4: Mouse thymus \u003cbr\u003e\n Lane 5: Mouse spleen \u003cbr\u003e\n Lane 6: Jurkat \u003cbr\u003e\n Lane 7: TF-1 \u003cbr\u003e\n Lane 8: F9, ICC staining CD34 in hES cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CD34, CD34, CD34 antigen, CD34 molecule, CD34, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, Mucosialin, OTTHUMP00000034733, OTTHUMP00000034734,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: peptide\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979769450675,"sku":"BS90234-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979769483443,"sku":"BS90234-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a68d104f-150c-477b-a24f-e2b2e1a603a2.jpg?v=1705749069","url":"https:\/\/afsbio.com\/products\/cd34-polyclonal-antibody-bs90234","provider":"AFSBio Inc.","version":"1.0","type":"link"}