{"product_id":"cd35-polyclonal-antibody-ra23047","title":"CD35 Polyclonal Antibody - RA23047","description":"CD35 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA23047-50, RA23047-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: complement C3b\/C4b receptor 1 (Knops blood group) (CR1) Homo sapiens This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and\/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. Alternate allele-specific splice variants\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000, ELISA 1:10000-20000\n\nAlternative Names: complement component (3b\/4b) receptor 1\/2 (Knops blood group) \n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 1378\n\nProtein MW (KDa): 220\n\nSWISS: P17927\/Q2VPA4\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121185579187,"sku":"RA23047-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121185611955,"sku":"RA23047-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_db10b3e6-8ab9-403c-a9b7-92e743567ef0.png?v=1773344955","url":"https:\/\/afsbio.com\/products\/cd35-polyclonal-antibody-ra23047","provider":"AFSBio Inc.","version":"1.0","type":"link"}