{"product_id":"cd38-polyclonal-antibody-bs90238","title":"CD38 Polyclonal Antibody-BS90238","description":"\u003cp\u003eCD38 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90238-50, BS90238-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P28907(Human)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000\u003cbr\u003e\nIHC:1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lymphocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabolites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD38 polyclonal antibody detects endogenous levels of CD38 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 40\/50 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of CD38 on different lysates using anti-CD38 antibody at 1\/1,000 dilution. \u003cbr\u003e\n Positive control: \u003cbr\u003e\n Lane 1: THP-1 \u003cbr\u003e\n Lane 2: Raji, Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD38 antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ADPRC 1, cADPr hydrolase 1, CD38, Acute lymphoblastic leukemia cells antigen CD38, ADP ribosyl cyclase 1, ADP ribosyl cyclase, ADP ribosyl cyclase\/cyclic ADP-ribose hydrolase, ADP-ribosyl cyclase 1, ADPRC 1, ADPRC1, cADPr hydrolase 1, CD 38, CD38, CD38 antigen (p45), CD38 antigen, CD38 molecule, Cd38-rs1, CD38, CD38H, Cyclic ADP ribose hydrolase, Cyclic ADP ribose hydrolase 1, Cyclic ADP-ribose hydrolase 1, EC 3.2.2.5, Ecto nicotinamide adenine dinucleotide glycohydrolase, I-19, I19 (mouse), Lymphocyte differentiation antigen CD38, NAD(+) nucleosidase, NIM-R5 antigen, NIMR5 antigen (mouse), OTTHUMP00000158633, OTTHUMP00000217743, p45, T10,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979769614515,"sku":"BS90238-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979769647283,"sku":"BS90238-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2adb62a7-1a3f-42e7-87ff-54eecc252c4a.jpg?v=1705749073","url":"https:\/\/afsbio.com\/products\/cd38-polyclonal-antibody-bs90238","provider":"AFSBio Inc.","version":"1.0","type":"link"}