{"product_id":"cd3d-monoclonal-antibody-bt-mca4294","title":"CD3D Monoclonal Antibody - BT-MCA4294","description":"\u003cp\u003eCD3D Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4294-50, BT-MCA4294-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is part of the T-cell receptor\/CD3 complex (TCR\/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha\/beta or TCR gamma\/delta to form the TCR\/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative\/B-cell-positive\/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD3D\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1H12G5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD3D\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD3D (AA: 127-171) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 19kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P04234\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: T3D, IMD19, CD3-DELTA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 915\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238377480371,"sku":"BT-MCA4294-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238377513139,"sku":"BT-MCA4294-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1334c8a8-663f-4874-98bb-4fde5409d0cb.png?v=1769379488","url":"https:\/\/afsbio.com\/products\/cd3d-monoclonal-antibody-bt-mca4294","provider":"AFSBio Inc.","version":"1.0","type":"link"}