{"product_id":"cd4-monoclonal-antibody-bt-mca4293","title":"CD4 Monoclonal Antibody - BT-MCA4293","description":"\u003cp\u003eCD4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4293-50, BT-MCA4293-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD4\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3A12A5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD4 (AA: 26-170) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 51kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P01730\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: IMD79, OKT4D, CD4mut\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 920\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238381904051,"sku":"BT-MCA4293-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238381936819,"sku":"BT-MCA4293-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_013963e7-7d42-463f-bd25-ef72f3c66987.png?v=1769379594","url":"https:\/\/afsbio.com\/products\/cd4-monoclonal-antibody-bt-mca4293","provider":"AFSBio Inc.","version":"1.0","type":"link"}