{"product_id":"cd45-8c1-monoclonal-antibody-mb3167","title":"CD45 (8C1) Monoclonal Antibody-MB3167","description":"\u003cp\u003eCD45 (8C1) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3167-50, MB3167-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P06800\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 145 kDa; Observed MW: 145 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunofluorescence analysis of CD45 in Human livercancer tissue using CD45 antibody, and DAPI., Immunohistochemical analysis of paraffin-embedded Human tonsils using CD45 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Negative control was used by secondary antibody only., Western blot analysis of CD45 in Jurkat lysates using CD45 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: GP180; L CA; CD45 antigen\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide of CD45\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42999926980787,"sku":"MB3167-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42999927013555,"sku":"MB3167-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_9054e0cf-8af5-464d-a387-e3b9f3f06aae.jpg?v=1706358190","url":"https:\/\/afsbio.com\/products\/cd45-8c1-monoclonal-antibody-mb3167","provider":"AFSBio Inc.","version":"1.0","type":"link"}