{"product_id":"cd48-polyclonal-antibody-ncp0213p","title":"CD48 Polyclonal Antibody-NCP0213P","description":"\u003cp\u003eCD48 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0213P-50, NCP0213P-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P09326\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000~1:2000\u003cbr\u003e\nIF  1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD48 polyclonal antibody detects endogenous levels of CD48 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 48 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD48 polyclonal antibody at 1:1000 dilution\u003cbr\u003e\n Lane 1: LOVO whole cell lysate (30ug)\u003cbr\u003e\n Lane 2: L02 cell membrane lysate (30ug)\u003cbr\u003e\n Lane 3: MCF-7 whole cell lysate (30ug)\u003cbr\u003e\n Lane 4: PMVEC whole cell lysate (20ug), Immunofluorescence analysis of MCF-7 cells using CD48 pAb at dilution of 1:200.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD_antigen: CD48; CD48; BCM1; BLAST1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD48.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989584875699,"sku":"NCP0213P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989584908467,"sku":"NCP0213P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_7b34761a-b491-4400-937e-0e77b73b9a2f.jpg?v=1706095789","url":"https:\/\/afsbio.com\/products\/cd48-polyclonal-antibody-ncp0213p","provider":"AFSBio Inc.","version":"1.0","type":"link"}