{"product_id":"cd49e-monoclonal-antibody-bt-mca3960","title":"CD49E Monoclonal Antibody - BT-MCA3960","description":"\u003cp\u003eCD49E Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3960-50, BT-MCA3960-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CD49E\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8D1G12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CD49E\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CD49E (AA: extra 111-253) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 114.5kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P08648\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ITGA5, FNRA, VLA-5, VLA5A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3678\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238540632243,"sku":"BT-MCA3960-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238540665011,"sku":"BT-MCA3960-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c12b4b67-246f-4344-bdba-f407213fc78f.png?v=1769382371","url":"https:\/\/afsbio.com\/products\/cd49e-monoclonal-antibody-bt-mca3960","provider":"AFSBio Inc.","version":"1.0","type":"link"}