{"product_id":"cd59-polyclonal-antibody-ncp0217p","title":"CD59 Polyclonal Antibody-NCP0217P","description":"\u003cp\u003eCD59 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: NCP0217P-50, NCP0217P-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P13987\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000~1:2000\u003cbr\u003e\nIF  1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and\/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD59 polyclonal antibody detects endogenous levels of CD59 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~17 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD59 polyclonal antibody at 1:1000 dilution\u003cbr\u003e\n Lane 1: MCF-7 cell membrane lysate (25ug)\u003cbr\u003e\n Lane 2: A549 cell membrane lysate (25ug)\u003cbr\u003e\n Lane 3: L02 cell membrane lysate (25ug), Immunofluorescence analysis of MCF-7 cells using CD59 pAb at dilution of 1:200.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human CD59.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989585006771,"sku":"NCP0217P-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989585039539,"sku":"NCP0217P-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_6984065f-2762-498a-927b-729da86ae938.jpg?v=1706095793","url":"https:\/\/afsbio.com\/products\/cd59-polyclonal-antibody-ncp0217p","provider":"AFSBio Inc.","version":"1.0","type":"link"}