{"product_id":"cd62p-monoclonal-antibody-mb65798","title":"CD62P Monoclonal Antibody-MB65798","description":"\u003cp\u003eCD62P Monoclonal Antibody\u003c\/p\u003e \n\n\u003cp\u003eCatalogue Numbers: MB65798-50, MB65798-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P16109\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IF (1\/50 - 1\/200)\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD62P\/P-Selectin is a type-I transmembrane glycoprotein that is largely expressed and stored in intracellular granules by resting platelets, megakaryocytes, and vascular endothelial cells. The restricted expression pattern of CD62P\/P-Selectin positions this molecule as a key regulator of hemostasis, thrombosis, and inflammation. Platelets and endothelial cells that become activated in response to proinflammatory cytokines express CD62P\/P-Selectin on the cell surface, which serves as an adhesion receptor to facilitate recruitment of leukocytes to sites of inflammation. CD62P\/P-Selectin has also been implicated in cancer cell metastasis by promoting the adhesion of tumor cells in circulation to activated platelets and endothelial cells .\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The monoclonal antibody  was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes human CD62P\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Flow cytometric analysis of human platelets treated with Thrombin using Anti-CD62P Antibody, followed by anti-mouse IgG PE.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: GMRP; GRMP; P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD antigen CD62P\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Native purified human CD62P.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908738289843,"sku":"MB65798-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908738322611,"sku":"MB65798-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_92d8a4cc-5a0b-43ab-bb5a-1154ef6a0cc5.jpg?v=1703006479","url":"https:\/\/afsbio.com\/products\/cd62p-monoclonal-antibody-mb65798","provider":"AFSBio Inc.","version":"1.0","type":"link"}