{"product_id":"cd73-monoclonal-antibody-mb65802","title":"CD73 Monoclonal Antibody-MB65802","description":"\u003cp\u003eCD73 Monoclonal Antibody\u003c\/p\u003e \n\n\u003cp\u003eCatalogue Numbers: MB65802-50, MB65802-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P21589\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IF (1\/50 - 1\/200)\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ecto-5'-nucleotidase (NT5E, also called CD73) is a 70 kDa glycosyl phosphatidylinositol-anchored, membrane-bound glycoprotein that catalyzes the hydrolysis of extracellular nucleoside monophosphates into bioactive nucleosides. NT5E catalyzes the terminal step of extracellular adenosine formation from adenosine monophosphate, which drives the regulation of extracellular adenosine levels and the downstream activation of the four G protein-coupled adenosine receptors. Binding of hypoxia-inducible factor (HIF-1) to the NT5E gene promoter leads to upregulation of NT5E during hypoxia. The biological roles of NT5E include lymphocyte adhesion, fibrosis, and the regulation of nociception.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The monoclonal antibody  was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes human CD73\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Flow cytometric analysis of human peripheral blood lymphocytes using Anti-CD73 Antibody, followed by anti-mouse IgG PE.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 63 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: NT5; NTE; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; CD antigen CD73\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Native purified human CD73.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42908738814131,"sku":"MB65802-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42908738846899,"sku":"MB65802-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_25f7f54a-8784-4038-9f53-627bf6260dc3.jpg?v=1703006487","url":"https:\/\/afsbio.com\/products\/cd73-monoclonal-antibody-mb65802","provider":"AFSBio Inc.","version":"1.0","type":"link"}