{"product_id":"cd8b-polyclonal-antibody-bs60358-b","title":"CD8B Polyclonal Antibody-BS60358-B","description":"\u003cp\u003eCD8B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS60358-B-50, BS60358-B-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P10966\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000~1:2000\u003cbr\u003e\nIHC: 1:50~1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: The T cell receptor (TCR) is a heterodimer composed of either α and β or γ and δ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (αα or αβ) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CD8B polyclonal antibody detects endogenous levels of CD8B protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 30kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of CD8B polyclonal antibody at 1:1000 dilution\u003cbr\u003e\n Lane 1: The spleen tissue lysate of Mouse (40ug)\u003cbr\u003e\n Lane 2: Myla2059 whole cell lysate (40ug), Immunohistochemistry of paraffin-embedded Human stomach cancer using CD8B antibody at dilution of 1:50 (40x lens).\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: T-cell surface glycoprotein CD8 beta chain; CD8b; CD8B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human CD8B.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42975432573107,"sku":"BS60358-B-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42975432605875,"sku":"BS60358-B-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3c6ed4a4-536d-47f6-be70-e168b010eb0f.jpg?v=1705665977","url":"https:\/\/afsbio.com\/products\/cd8b-polyclonal-antibody-bs60358-b","provider":"AFSBio Inc.","version":"1.0","type":"link"}