{"product_id":"cdc23-rabbit-pab-es1925","title":"Cdc23 rabbit pAb - ES1925","description":"\u003cp\u003eCdc23 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1925-50, ES1925-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2\/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: CDC23; ANAPC8; Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Monkey\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human APC8. AA range:251-300\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 69kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 8697\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UJX2\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: intracellular, nucleoplasm, anaphase-promoting complex, cytosol,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202044747955,"sku":"ES1925-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202044780723,"sku":"ES1925-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_c93016d5-de12-4696-b73b-cbf984ec2bc3.png?v=1767120586","url":"https:\/\/afsbio.com\/products\/cdc23-rabbit-pab-es1925","provider":"AFSBio Inc.","version":"1.0","type":"link"}