{"product_id":"cdc25a-polyclonal-antibody-bt-ap01579","title":"Cdc25A Polyclonal Antibody - BT-AP01579","description":"\u003cp\u003eCdc25A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01579-20, BT-AP01579-50, BT-AP01579-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for CDC25A.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDC25A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cdc25A Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 59087\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P30304; Mouse: P48964; Rat: P48965\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 993; Rat: 171102\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240185422003,"sku":"BT-AP01579-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240185454771,"sku":"BT-AP01579-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240185487539,"sku":"BT-AP01579-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_89df5b78-e87b-42e2-96dd-abb8ab2a9cad.png?v=1769404778","url":"https:\/\/afsbio.com\/products\/cdc25a-polyclonal-antibody-bt-ap01579","provider":"AFSBio Inc.","version":"1.0","type":"link"}