{"product_id":"cdc25b-polyclonal-antibody-bt-ap01581","title":"Cdc25B Polyclonal Antibody - BT-AP01581","description":"\u003cp\u003eCdc25B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01581-20, BT-AP01581-50, BT-AP01581-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CDC25B (cell division cycle 25B) is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDC25B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cdc25B Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 64987\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P30305; Mouse: P30306; Rat: P48966\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CDC25B; CDC25HU2; M-phase inducer phosphatase 2; Dual specificity phosphatase Cdc25B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 994; Mouse: 12531; Rat: 171103\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240185618611,"sku":"BT-AP01581-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240185651379,"sku":"BT-AP01581-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240185684147,"sku":"BT-AP01581-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3b2e1d86-7ae0-4d17-8f67-64effc8d5a91.png?v=1769404781","url":"https:\/\/afsbio.com\/products\/cdc25b-polyclonal-antibody-bt-ap01581","provider":"AFSBio Inc.","version":"1.0","type":"link"}