{"product_id":"cdc42ep1-polyclonal-antibody-bs90274","title":"CDC42EP1 Polyclonal Antibody-BS90274","description":"\u003cp\u003eCDC42EP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90274-50, BS90274-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q00587(Human)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:2,000\u003c\/p\u003e\n\n\u003cp\u003eBackground: MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42\/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of CDC42EP1 on differentLysates using anti-CDC42EP1 antibody at 1\/1,000 dilution. Positive control: Lane 1: HUVEC Lane 2: Hela\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 60 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CDC42EP1 polyclonal antibody detects endogenous levels of CDC42EP1 protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CDC42EP1, 55 kDa bone marrow stromal\/endothelial cell protein, Binder of Rho GTPases 5, Bone marrow stromal\/endothelial cell protein, 55-KD, BORG 5, BORG5, BORG5, CDC42 effector protein (Rho GTPase binding) 1, Cdc42 effector protein 1, Cdc42ep1, CEP 1, CEP1, MGC15316, MSE 55, MSE55, OTTHUMP00000028709, Serum constituent protein, Serum protein MSE55,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939198570675,"sku":"BS90274-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939198603443,"sku":"BS90274-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b4d5ceff-714c-462b-ad5c-db2bef489c9f.jpg?v=1704544961","url":"https:\/\/afsbio.com\/products\/cdc42ep1-polyclonal-antibody-bs90274","provider":"AFSBio Inc.","version":"1.0","type":"link"}