{"product_id":"cdc42ep5-polyclonal-antibody-bt-ap01595","title":"Cdc42EP5 Polyclonal Antibody - BT-AP01595","description":"\u003cp\u003eCdc42EP5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01595-20, BT-AP01595-50, BT-AP01595-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42\/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDC42EP5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cdc42EP5 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 15207\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6NZY7; Mouse: Q9Z0X0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CDC42EP5; BORG3; CEP5; Cdc42 effector protein 5; Binder of Rho GTPases 3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 148170; Mouse: 58804\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240186896563,"sku":"BT-AP01595-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240186929331,"sku":"BT-AP01595-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240186962099,"sku":"BT-AP01595-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f39af6e2-9f35-41a5-90b2-c670f73074ef.png?v=1769404801","url":"https:\/\/afsbio.com\/products\/cdc42ep5-polyclonal-antibody-bt-ap01595","provider":"AFSBio Inc.","version":"1.0","type":"link"}