{"product_id":"cdc46-rabbit-polyclonal-antibody-es1933","title":"CDC46 Rabbit Polyclonal Antibody - ES1933","description":"\u003cp\u003eCDC46 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1933-50, ES1933-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1\/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MCM5, CDC46, DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human MCM5. AA range:21-70\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: CDC46\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CDC46 Polyclonal Antibody detects endogenous levels of CDC46 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Cervix, Cervix carcinoma, Lymph, Placenta, Spleen, Thymus, Tongue\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 90kD\u003c\/p\u003e\n\n\u003cp\u003eFields: DNA replication, Cell cycle\u003c\/p\u003e\n\n\u003cp\u003eFunction: Similarity: Belongs to the MCM family\u003cbr\u003e\nSimilarity: Contains 1 MCM domain\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Nucleus Chromosome Cytoplasm, cytosol Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: MCM5\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: DNA replication licensing factor MCM5\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P49718\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315877630131,"sku":"ES1933-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315877662899,"sku":"ES1933-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/cdc46-rabbit-polyclonal-antibody-es1933","provider":"AFSBio Inc.","version":"1.0","type":"link"}