{"product_id":"cdh3-polyclonal-antibody-bt-ap01449","title":"CDH3 Polyclonal Antibody - BT-AP01449","description":"\u003cp\u003eCDH3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01449-20, BT-AP01449-50, BT-AP01449-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Signal transduction; Tags and cell markers; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDH3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cadherin-3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P22223; Mouse: P10287\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cadherin-3 (Placental cadherin;P-cadherin; Cadherin-3; Placental cadherin; P-cadherin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1001; Mouse: 12560\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238962487475,"sku":"BT-AP01449-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238962520243,"sku":"BT-AP01449-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238962553011,"sku":"BT-AP01449-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7e006efd-35d9-49a2-be93-4f9fbf7a4b1a.png?v=1769387313","url":"https:\/\/afsbio.com\/products\/cdh3-polyclonal-antibody-bt-ap01449","provider":"AFSBio Inc.","version":"1.0","type":"link"}