{"product_id":"cdkn1c-monoclonal-antibody-bt-mca3411","title":"CDKN1C Monoclonal Antibody - BT-MCA3411","description":"\u003cp\u003eCDKN1C Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3411-50, BT-MCA3411-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin\/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDKN1C\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3E3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CDKN1C\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 57kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P49918\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: BWS, WBS, p57, BWCR, KIP2, CDKN1C\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1028\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238425944243,"sku":"BT-MCA3411-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238425977011,"sku":"BT-MCA3411-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_41fe641b-9ae3-47be-a2ce-430c69b91a85.png?v=1769380602","url":"https:\/\/afsbio.com\/products\/cdkn1c-monoclonal-antibody-bt-mca3411","provider":"AFSBio Inc.","version":"1.0","type":"link"}