{"product_id":"cdkn2a-p16ink4a-monoclonal-antibody-mb10721","title":"CDKN2A\/p16INK4a Monoclonal Antibody-MB10721","description":"\u003cp\u003eCDKN2A\/p16INK4a Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10721-50, MB10721-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P51480\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 18 kDa; Observed MW: 18 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of CDKN2A\/p16INK4a in 3T3 lysates using CDKN2A antibody., Western blot analysis of CDKN2A\/p16INK4a in C6 lysates using CDKN2A\/p16INK4a antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cdkn2a; P16ink4a; Cyclin-dependent kinase 4 inhibitor A (CDK4I); p16-INK4a ; p16-INK4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of mouse CDKN2A\/p16INK4a\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970490994867,"sku":"MB10721-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970491027635,"sku":"MB10721-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_14c35778-903c-4902-b0b2-1970fd4c3d19.jpg?v=1705526284","url":"https:\/\/afsbio.com\/products\/cdkn2a-p16ink4a-monoclonal-antibody-mb10721","provider":"AFSBio Inc.","version":"1.0","type":"link"}