{"product_id":"cemp1-polyclonal-antibody-bs66121","title":"CEMP1 Polyclonal Antibody-BS66121","description":"\u003cp\u003eCEMP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS66121-50, BS66121-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q6PRD7\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: ELISA IHC IF ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: ELISA: 1:5000-1:10000\u003cbr\u003e\nIHC: 1:100-1:500\u003cbr\u003e\nIF: 1:100-1:500\u003cbr\u003e\nICC: 1:100-1:500\u003c\/p\u003e\n\n\u003cp\u003eBackground: A mineralized connective tissue known as cementum covers the root surfaces of teeth and is required for maturation of periodontal tissue. CEMP1 (cementum protein 1), also designated CP23 or cementoblastoma-derived protein 1, is a 247 amino acid nuclear and cytoplasmic protein that is thought to regulate cementoblast behavior. Expressed specifically in periodontal ligament and cementum, CEMP1 may play a role in differentiation and mineralization of non-osteogenic cells. The gene encoding CEMP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CEMP1 polyclonal antibody detects endogenous levels of CEMP1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 26 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cementoblastoma-derived protein 1;  Cementum protein 1;  Cementum protein 23;  CEMP1;  CEMP1_HUMAN;  CP-23;  CP23\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human CEMP1: 151-247\/247\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42899700809907,"sku":"BS66121-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42899700842675,"sku":"BS66121-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_07ee761f-7497-4e28-9d7d-b604da7a107f.jpg?v=1702661242","url":"https:\/\/afsbio.com\/products\/cemp1-polyclonal-antibody-bs66121","provider":"AFSBio Inc.","version":"1.0","type":"link"}