{"product_id":"cenp-a-polyclonal-antibody-bt-ap01672","title":"CENP-A Polyclonal Antibody - BT-AP01672","description":"\u003cp\u003eCENP-A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01672-20, BT-AP01672-50, BT-AP01672-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CENPA\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CENP-A Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 15991\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49450; Mouse: O35216\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CENPA; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENP-A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1058\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240191254707,"sku":"BT-AP01672-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240191287475,"sku":"BT-AP01672-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240191320243,"sku":"BT-AP01672-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_14f11c35-346e-43e0-8ac1-85bba7185f2d.png?v=1769404875","url":"https:\/\/afsbio.com\/products\/cenp-a-polyclonal-antibody-bt-ap01672","provider":"AFSBio Inc.","version":"1.0","type":"link"}