{"product_id":"cerkl-polyclonal-antibody-e-ab-91393","title":"CERKL Polyclonal Antibody - E-AB-91393","description":"\u003cp\u003eCERKL Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91393-60, E-AB-91393-120, E-AB-91393-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CERKL\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CERKL; RP26\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q49MI3\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CERKL\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 19kDa, 24kDa, 42-62kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 63kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146602119347,"sku":"E-AB-91393-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146602152115,"sku":"E-AB-91393-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146602184883,"sku":"E-AB-91393-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8190e56a-d3d7-4b64-abba-3a7b710057fa.png?v=1710298231","url":"https:\/\/afsbio.com\/products\/cerkl-polyclonal-antibody-e-ab-91393","provider":"AFSBio Inc.","version":"1.0","type":"link"}