{"product_id":"chd3-c-term-mouse-monoclonal-antibody-ra10975","title":"CHD3 (C-term) Mouse Monoclonal Antibody - RA10975","description":"\u003cp\u003eCHD3 (C-term) Mouse Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA10975-50, RA10975-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: chromodomain helicase DNA binding protein 3 (CHD3) Homo sapiens This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase\/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2\/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; FC\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 1107\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 260\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q12873\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119025774771,"sku":"RA10975-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119025807539,"sku":"RA10975-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7a93fc52-eae3-4b85-b213-fdee444b8275.png?v=1773344394","url":"https:\/\/afsbio.com\/products\/chd3-c-term-mouse-monoclonal-antibody-ra10975","provider":"AFSBio Inc.","version":"1.0","type":"link"}