{"product_id":"chd3-monoclonal-antibody-bt-mca3628","title":"CHD3 Monoclonal Antibody - BT-MCA3628","description":"\u003cp\u003eCHD3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3628-50, BT-MCA3628-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase\/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2\/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling, Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CHD3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2G4\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CHD3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human CHD3 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 226kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q12873\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ZFH, Mi-2a, Mi2-ALPHA, CHD3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1107\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238632874163,"sku":"BT-MCA3628-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238632906931,"sku":"BT-MCA3628-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1544486e-c8ec-494d-b92e-6d9b08fea6fe.png?v=1769383260","url":"https:\/\/afsbio.com\/products\/chd3-monoclonal-antibody-bt-mca3628","provider":"AFSBio Inc.","version":"1.0","type":"link"}