{"product_id":"chd4-rabbit-pab-a11574","title":"CHD4 Rabbit pAb - A11574","description":"\u003cp\u003eCHD4 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A11574-20, A11574-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the SNF2\/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 218kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 280kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1108\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q14839\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CHD-4; Mi-2b; SIHIWES; Mi2-BETA; CHD4\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:100 - 1:200 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Chromatin Remodeling, Immunology Inflammation.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CHD4\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189500403891,"sku":"A11574-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189500436659,"sku":"A11574-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_0ea217c0-4fb9-4b5e-ba7f-886f1dd3710c.png?v=1766428421","url":"https:\/\/afsbio.com\/products\/chd4-rabbit-pab-a11574","provider":"AFSBio Inc.","version":"1.0","type":"link"}