{"product_id":"chd8-polyclonal-antibody-ra31597","title":"CHD8 Polyclonal Antibody - RA31597","description":"\u003cp\u003eCHD8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA31597-50, RA31597-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: chromodomain helicase DNA binding protein 8 (CHD8) Homo sapiens This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 57680\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 283\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9HCK8\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120441712819,"sku":"RA31597-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120441745587,"sku":"RA31597-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_36cb906b-9ee0-4239-bf59-74e6969fc8f3.png?v=1773365574","url":"https:\/\/afsbio.com\/products\/chd8-polyclonal-antibody-ra31597","provider":"AFSBio Inc.","version":"1.0","type":"link"}