{"product_id":"chic2-rabbit-polyclonal-antibody-es17481","title":"CHIC2 Rabbit Polyclonal Antibody - ES17481","description":"\u003cp\u003eCHIC2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES17481-50, ES17481-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human CHIC2 AA range: 111-161\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: CHIC2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of CHIC2 at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 18kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Disease: A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4, 12)(q12, p13) with ETV6\u003cbr\u003e\nPTM: Palmitoylation in the CHIC motif is required for membrane association\u003cbr\u003e\nSimilarity: Belongs to the CHIC family\u003cbr\u003e\nSubcellular Location: Also present at a Golgi-like vesicular compartment and at scattered vesicles\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cell membrane Cytoplasmic vesicle Also present at a Golgi-like vesicular compartment and at scattered vesicles\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: CHIC2 BTL\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: CHIC2\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 74277\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q9D9G3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315603067059,"sku":"ES17481-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315603099827,"sku":"ES17481-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/chic2-rabbit-polyclonal-antibody-es17481","provider":"AFSBio Inc.","version":"1.0","type":"link"}