{"product_id":"chit1-monoclonal-antibody-bt-mca4304","title":"CHIT1 Monoclonal Antibody - BT-MCA4304","description":"\u003cp\u003eCHIT1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4304-50, BT-MCA4304-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CHIT1\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1D9G2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CHIT1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 52kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q13231\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Chitotriosidase, CHI3, CHIT, FLJ00314, MGC125322, CHIT1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 1118\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238428303539,"sku":"BT-MCA4304-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238428336307,"sku":"BT-MCA4304-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_34e4aca5-8a9e-49d1-9749-efea008cf419.png?v=1769380654","url":"https:\/\/afsbio.com\/products\/chit1-monoclonal-antibody-bt-mca4304","provider":"AFSBio Inc.","version":"1.0","type":"link"}