{"product_id":"chk2-monoclonal-antibody-mb10732","title":"Chk2 Monoclonal Antibody-MB10732","description":"\u003cp\u003eChk2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10732-50, MB10732-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O96017\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: These are known to be preferred sites for phosphorylation by ATM\/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM\/ATR. The SQ\/TQ cluster domain, therefore, seems to have a regulatory function.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunocytochemistry analysis of Chk2 in HCT116 using Chk2 antibody, and DAPI., Western blot analysis of Chk2 in Jurkat lysates using Chk2 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CHEK2; CDS1; CHK2; RAD53; Serine\/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human Chk2\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42970491322547,"sku":"MB10732-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42970491355315,"sku":"MB10732-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fbfdb5c0-807a-4daf-a755-361a760a5347.jpg?v=1705526295","url":"https:\/\/afsbio.com\/products\/chk2-monoclonal-antibody-mb10732","provider":"AFSBio Inc.","version":"1.0","type":"link"}