{"product_id":"chn2-polyclonal-antibody-e-ab-92958","title":"CHN2 Polyclonal Antibody - E-AB-92958","description":"\u003cp\u003eCHN2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92958-60, E-AB-92958-120, E-AB-92958-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CHN2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CHN2; ARHGAP3; BCH; CHN2-3; RHOGAP3\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P52757\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester\/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human CHN2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27kDa\/31kDa\/33kDa\/37kDa\/38kDa\/53kDa\/62kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 54kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43145978118323,"sku":"E-AB-92958-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43145978151091,"sku":"E-AB-92958-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43145978183859,"sku":"E-AB-92958-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_782f5f43-ac7a-4f50-afba-94259a89f46f.png?v=1710289162","url":"https:\/\/afsbio.com\/products\/chn2-polyclonal-antibody-e-ab-92958","provider":"AFSBio Inc.","version":"1.0","type":"link"}