{"product_id":"chop-mouse-monoclonal-antibody-2b1-bt-mca0020","title":"CHOP mouse Monoclonal Antibody (2B1) - BT-MCA0020","description":"\u003cp\u003eCHOP mouse Monoclonal Antibody (2B1)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0020-20, BT-MCA0020-50, BT-MCA0020-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the CCAAT\/enhancer-binding protein (C\/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C\/EBP members, such as C\/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Stem cells; Developmental biology; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: DDIT3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ICC, IHC-p\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Rat,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: DDIT3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35638; Mouse: P35639; Rat: Q62857\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DDIT3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1649\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240026103987,"sku":"BT-MCA0020-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240026136755,"sku":"BT-MCA0020-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240026169523,"sku":"BT-MCA0020-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1da73680-1f62-4ecb-8b5b-b31e571c79de.png?v=1769402328","url":"https:\/\/afsbio.com\/products\/chop-mouse-monoclonal-antibody-2b1-bt-mca0020","provider":"AFSBio Inc.","version":"1.0","type":"link"}