{"product_id":"chp2-polyclonal-antibody-bt-ap01780","title":"CHP2 Polyclonal Antibody - BT-AP01780","description":"\u003cp\u003eCHP2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP01780-20, BT-AP01780-50, BT-AP01780-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CHP2 product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+\/H+ exchange activity. Calcineurin like EF-hand protein 2 shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin\/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). CHP2 was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CHP2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: CHP2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 22452\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O43745; Mouse: Q9D869; Rat: Q810D1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CHP2; HCA520; Calcineurin B homologous protein 2; Hepatocellular carcinoma-associated antigen 520\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 63928; Rat: 308965\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240198627507,"sku":"BT-AP01780-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240198660275,"sku":"BT-AP01780-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240198693043,"sku":"BT-AP01780-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c175d69a-e14e-4cf6-8d11-f65501da7854.png?v=1769404988","url":"https:\/\/afsbio.com\/products\/chp2-polyclonal-antibody-bt-ap01780","provider":"AFSBio Inc.","version":"1.0","type":"link"}