{"product_id":"chromogranin-a-polyclonal-antibody-e-ab-40339","title":"Chromogranin A Polyclonal Antibody - E-AB-40339","description":"\u003cp\u003eChromogranin A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-40339-60, E-AB-40339-120, E-AB-40339-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Chromogranin A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: beta Granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHG A; Chga; chromofungin; Chromogranin A; Chromogranin A parathyroid secretory protein 1; Chromogranin A precursor; ChromograninA; CMGA; ER-37; Pancreastatin; Parastatin; Parathyroid secretory protein 1; Pituitary secretory protein I; Secretory protein I; SP I; SP-I; SP1; SPI; Vasostatin; Vasostatin I; Vasostatin II\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P26339\u003c\/p\u003e\n\n\u003cp\u003eBackground: Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant Mouse Chromogranin-A protein\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen Affinity Purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000  IHC 1:100-1:300\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 51 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 51 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146027761843,"sku":"E-AB-40339-60","price":175.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146027794611,"sku":"E-AB-40339-120","price":322.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146027827379,"sku":"E-AB-40339-200","price":532.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e250b374-6784-4c26-a82a-276d5706ea50.png?v=1710290092","url":"https:\/\/afsbio.com\/products\/chromogranin-a-polyclonal-antibody-e-ab-40339","provider":"AFSBio Inc.","version":"1.0","type":"link"}