{"product_id":"chst2-rabbit-polyclonal-antibody-es1981","title":"CHST2 Rabbit Polyclonal Antibody - ES1981","description":"\u003cp\u003eCHST2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1981-50, ES1981-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This locus encodes a sulfotransferase protein. The encoded enzyme catalyzes the sulfation of a nonreducing N-acetylglucosamine residue, and may play a role in biosynthesis of 6-sulfosialyl Lewis X antigen. [provided by RefSeq, Aug 2011],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CHST2, GN6ST, Carbohydrate sulfotransferase 2, Galactose\/N-acetylglucosamine\/N-acetylglucosamine 6-O-sulfotransferase 2, GST-2, N-acetylglucosamine 6-O-sulfotransferase 1, GlcNAc6ST-1, Gn6ST-1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human CHST2. AA range:1-50\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: CHST2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: CHST2 Polyclonal Antibody detects endogenous levels of CHST2 protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Widely expressed, Highly expressed in bone marrow, peripheral blood leukocytes, spleen, brain, spinal cord, ovary and placenta, Expressed by high endothelial cells (HEVs) and leukocytes,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 58kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Glycosaminoglycan biosynthesis - keratan sulfate\u003c\/p\u003e\n\n\u003cp\u003eFunction: Caution: It is uncertain whether Met-1 or Met-48 is the initiator\u003cbr\u003e\nFunction: Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as L-selectin ligands. L-selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of L-selectin ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains\u003cbr\u003e\nInduction: Up-regulated upon cytokine activation\u003cbr\u003e\nOnline Information: GlycoGene database,Similarity: Belongs to the sulfotransferase 1 family.\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Golgi apparatus, trans-Golgi network membrane, Single-pass type II membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: CHST2\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Carbohydrate sulfotransferase 2\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q80WV3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315883233459,"sku":"ES1981-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315883266227,"sku":"ES1981-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/chst2-rabbit-polyclonal-antibody-es1981","provider":"AFSBio Inc.","version":"1.0","type":"link"}