{"product_id":"chymase-rabbit-pab-es3853","title":"Chymase rabbit pAb - ES3853","description":"\u003cp\u003eChymase rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3853-50, ES3853-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: chymase 1 (CMA1) Homo sapiens This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: CMA1; CYH; CYM; Chymase; Alpha-chymase; Mast cell protease I\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthesized peptide derived from the Internal region of human Chymase.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 27kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 1215\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P23946\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted. Cytoplasmic granule. Mast cell granules.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202159435955,"sku":"ES3853-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202159468723,"sku":"ES3853-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_e2d38cd9-5e5c-4c1a-b68e-985d50ad474d.png?v=1767123282","url":"https:\/\/afsbio.com\/products\/chymase-rabbit-pab-es3853","provider":"AFSBio Inc.","version":"1.0","type":"link"}