{"product_id":"cidea-polyclonal-antibody-bt-ap14969","title":"CIDEA Polyclonal Antibody - BT-AP14969","description":"\u003cp\u003eCIDEA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14969-20, BT-AP14969-50, BT-AP14969-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Cell biology; Epigenetics and nuclear signaling; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CIDEA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cell death activator CIDE-A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O60543; Mouse: O70302\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cell death activator CIDE-A;Cell death-inducing DFFA-like effector A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1149\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239094345907,"sku":"BT-AP14969-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239094378675,"sku":"BT-AP14969-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239094411443,"sku":"BT-AP14969-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_86244fb0-f672-414d-95b2-849d42137e4a.png?v=1769389040","url":"https:\/\/afsbio.com\/products\/cidea-polyclonal-antibody-bt-ap14969","provider":"AFSBio Inc.","version":"1.0","type":"link"}